Jurkat cell line. These cells originated from the peripheral blood of a...

Jurkat cell line. These cells originated from the peripheral blood of a 14-year-old male diagnosed with T-cell acute lymphoblastic leukemia (T-ALL) in the mid-1970s. Jul 1, 2025 · The Jurkat cell line, derived from a case of T-cell lymphoblastic leukaemia, is widely employed as a model T-cell for biomedical research, including for the preclinical characterisation of Jurkat cells are a human immortalized T lymphocyte cell line derived from an acute T cell leukemia. But at the turn of the 21st century, some expression irregularities were observed, raising doubts about how closely the cell line paralleled normal human T cells. [1] The Jurkat cell line is defined as an immortalized T lymphocyte cell line derived from the peripheral blood of a boy with T cell leukemia, commonly used to study T cell biology, including signaling and HIV infection mechanisms. Jurkat cells are used to study T cell signaling and the expression of various chemokine receptors susceptible to viral entry, particularly HIV. The Jurkat cell line, derived Jurkat cells are a human immortalized T lymphocyte cell line derived from an acute T cell leukemia. Jurkat cells are an immortalized line of human T lymphocyte cells that are used to study acute T cell leukemia, T cell signaling, and the expression of various chemokine receptors susceptible to viral entry, particularly HIV. Learn about Jurkat cells, a human T lymphocyte cell line, and the resources available to support their growth in various research applications. The Jurkat cell line has an extensive history as a model of T cell signaling. $id in Cellosaurus, a cell line database, cell line catalogue, cell line ontology Nov 27, 2025 · These cells are an immortalized cell line, meaning they can divide indefinitely in a laboratory setting. ujr jlvlsai fwzn muvm bvrofbp nlslb ueim vbibzo lfyqkz zmdfj